:root {
      color-scheme: light dark;
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    .treatment-caution{margin-top:24px;padding:20px 22px;background:var(--surface-2);border-left:5px solid var(--teal);font-size:.86rem;color:var(--muted)}
    .treatment-caution strong{color:var(--ink)}
    .pipeline{display:grid;grid-template-columns:repeat(3,1fr);gap:20px}
    .pipeline article{background:var(--surface);padding:22px;border-bottom:4px solid var(--teal)}
    .pipeline h3{font-size:1.15rem;margin:10px 0}.pipeline p{color:var(--muted);font-size:.87rem;margin:0 0 13px}
    .search-panel{display:flex;gap:10px;align-items:center;margin:0 0 30px}
    .search-panel input{width:100%;padding:13px 15px;border:1px solid var(--line);background:var(--surface);color:var(--ink);border-radius:0;outline:none}
    .search-panel input:focus{border-color:var(--teal);box-shadow:0 0 0 3px color-mix(in srgb,var(--teal) 24%,transparent)}
    .empty{display:none;color:var(--muted);padding:20px;border:1px dashed var(--line)}
    footer{background:#031d35;color:#d9ecf0;padding:48px 0 70px;margin-top:20px}
    footer .wrap{display:grid;grid-template-columns:1fr 1fr;gap:60px}
    footer h2{font-size:1.6rem;margin-bottom:12px}footer p{color:#a9c0ba;font-size:.86rem;max-width:58ch}
    .sources{font-size:.76rem;color:#a9c0ba}.sources a{color:#d2e3df}
    .disclaimer{border-top:1px solid #28423d;padding-top:18px;margin-top:22px}
    .sponsor{grid-column:1/-1;border-top:1px solid #28423d;padding-top:34px;display:grid;grid-template-columns:minmax(220px,.7fr) minmax(0,1.3fr);gap:54px;align-items:start}
    .sponsor h2{font-size:clamp(1.55rem,2.4vw,2.1rem)}
    .sponsor-copy p{margin:0}
    .sponsor-form{display:grid;grid-template-columns:1fr 1fr;gap:17px 18px}
    .sponsor-form label{display:grid;gap:7px;color:#d2e3df;font-size:.78rem;font-weight:700}
    .sponsor-form .full{grid-column:1/-1}
    .sponsor-form .honeypot{position:absolute!important;left:-10000px!important;top:auto!important;width:1px!important;height:1px!important;overflow:hidden!important;opacity:0!important;pointer-events:none!important}
    .sponsor-form input,.sponsor-form textarea{width:100%;min-height:44px;border:1px solid #78938c;background:#0d201c;color:#edf6f2;padding:11px 12px;border-radius:0;outline:none}
    .sponsor-form textarea{min-height:126px;resize:vertical;line-height:1.5}
    .sponsor-form input::placeholder,.sponsor-form textarea::placeholder{color:#78938c}
    .sponsor-form input:focus,.sponsor-form textarea:focus{border-color:#7bddd3;box-shadow:0 0 0 3px rgba(101,213,202,.18)}
    .sponsor-form button{justify-self:start;border:0;background:#d2e3df;color:#071513;padding:11px 18px;font-weight:800;cursor:pointer}
    .sponsor-form button:hover{background:#fff}
    .sponsor-form button:focus-visible{outline:2px solid var(--focus);outline-offset:3px}
    .newsletter{grid-column:1/-1;border-top:1px solid #28423d;border-bottom:1px solid #28423d;padding:30px 0;display:grid;grid-template-columns:minmax(220px,.75fr) minmax(0,1.25fr);gap:54px;align-items:center}
    .newsletter h2{margin:0 0 8px}.newsletter p{margin:0}
    .newsletter-form{display:grid;grid-template-columns:minmax(0,1fr) auto;gap:10px;align-items:start}
    .newsletter-form input{width:100%;min-width:0;min-height:44px;border:1px solid #78938c;background:#0d201c;color:#edf6f2;padding:12px;border-radius:0;outline:none}
    .newsletter-form input::placeholder{color:#78938c}.newsletter-form input:focus{border-color:#7bddd3;box-shadow:0 0 0 3px rgba(101,213,202,.18)}
    .newsletter-form button{border:0;background:#d2e3df;color:#071513;padding:12px 18px;font-weight:800;cursor:pointer;white-space:nowrap}.newsletter-form button:hover{background:#fff}.newsletter-form button:focus-visible{outline:2px solid var(--focus);outline-offset:3px}
    .newsletter-form .honeypot{position:absolute!important;left:-10000px!important;width:1px!important;height:1px!important;opacity:0!important;pointer-events:none!important}
    .field-label{display:block;color:#d2e3df;font-size:.78rem;font-weight:700;margin-bottom:7px}
    .form-status{grid-column:1/-1;min-height:1.4em;margin:0!important;font-size:.78rem!important;color:#a9c0ba!important}.form-status.success{color:#8fe0b0!important}.form-status.error{color:#ff9a91!important;font-weight:700}
    input[aria-invalid="true"],textarea[aria-invalid="true"]{border-color:#ff9a91!important;box-shadow:0 0 0 3px rgba(255,154,145,.2)!important}
    .sponsor-form button,.newsletter-form button{min-height:44px}
    .legal{grid-column:1/-1;padding-top:4px}.legal-nav{display:flex;flex-wrap:wrap;gap:0 18px;padding:0 0 18px;border-bottom:1px solid #28423d}.legal-nav a{min-height:44px;display:inline-flex;align-items:center;color:#d2e3df;font-size:.8rem;font-weight:700}
    .legal details{border-bottom:1px solid #28423d}.legal summary{min-height:44px;cursor:pointer;padding:18px 0;font-family:"Libre Franklin",sans-serif;font-weight:700;color:#edf6f2;list-style:none}.legal summary::-webkit-details-marker{display:none}.legal summary::after{content:"+";float:right;color:#7bddd3;font-size:1.2rem}.legal details[open] summary::after{content:"−"}
    .legal-copy{padding:0 0 22px;max-width:92ch}.legal-copy h3{font-size:1rem;margin:20px 0 7px;color:#edf6f2}.legal-copy p,.legal-copy li{font-size:.78rem;color:#a9c0ba}.legal-copy ul{padding-left:19px}.legal-updated{font-size:.72rem;color:#78938c}
    .footer-bottom{grid-column:1/-1;display:flex;justify-content:space-between;gap:18px;align-items:center;padding-top:8px;color:#78938c;font-size:.72rem}.footer-bottom p{margin:0;font-size:.72rem}
    .mobile-only{display:none}
    @media(max-width:850px){
      .wrap{width:min(100% - 26px,720px)}
      .lead-layout{grid-template-columns:1fr;margin-top:14px}.hero{min-height:570px}.hero-slide img{object-position:66% center}.hero-slide::after{background:linear-gradient(0deg,rgba(1,22,24,.98) 0%,rgba(1,22,24,.88) 51%,rgba(1,22,24,.1) 100%)}.hero-copy{padding:28px 23px 76px;width:100%}.hero-controls{right:16px;bottom:16px}
      .news-desk{border-left:1px solid var(--line);border-top:0;display:grid;grid-template-columns:1fr 1fr;column-gap:24px}.desk-kicker,.evidence-key{grid-column:1/-1}.evidence-key{margin-top:0}
      .hero-title{font-size:2.45rem;max-width:13ch}.dek{font-size:.98rem}
      .section{padding:48px 0}.section-head{align-items:start;flex-direction:column}.news-grid{grid-template-columns:1fr 1fr}.story.feature{grid-column:1/-1}.story.feature img{height:280px}
      .testing-intro{grid-template-columns:1fr;gap:24px}.testing-intro img{height:250px}.method-grid,.lab-grid{grid-template-columns:1fr 1fr}
      .igl-mast,.igl-body,.evidence-mast,.evidence-body{grid-template-columns:1fr;gap:26px}.igl-mast,.evidence-mast{align-items:start}.igl-verdict,.evidence-verdict{max-width:640px}.igl-sidebar,.evidence-side{border-left:0;border-top:1px solid var(--line);padding:26px 0 0}.evidence-ladder,.grade-grid{grid-template-columns:1fr}
      .treatment-entry{grid-template-columns:1fr;gap:20px}.treatment-detail{grid-template-columns:1fr 1fr}.treatment-sources{grid-column:1/-1}
      .watchdog-grid{grid-template-columns:1fr}.pipeline{grid-template-columns:1fr 1fr}.pipeline article:last-child{grid-column:1/-1}
      footer .wrap{grid-template-columns:1fr;gap:25px}.sponsor{grid-column:auto;grid-template-columns:1fr;gap:22px;padding-top:28px}.newsletter{grid-column:auto;grid-template-columns:1fr;gap:18px}
    }
    @media(max-width:540px){
      .brand-mast .wrap{padding:12px 0 14px}.brand-mast .brand-home{width:min(100%,350px)}.brand-tagline{font-size:clamp(.94rem,4.5vw,1.08rem);letter-spacing:.025em;line-height:1.25;padding:0 8px}.utility .wrap{min-height:48px;gap:10px}.edition{line-height:1.15}.snapshot{display:none}.theme-toggle{padding:8px 10px}.theme-label{position:absolute!important;width:1px!important;height:1px!important;padding:0!important;margin:-1px!important;overflow:hidden!important;clip:rect(0,0,0,0)!important;white-space:nowrap!important;border:0!important}.topic-nav .wrap{gap:3px}.topic-nav button{font-size:.78rem;min-height:44px;padding:9px 10px}.hero-controls{right:8px;bottom:8px;padding:3px;gap:1px}.hero-dots{gap:0}.hero-arrow,.hero-dot,.hero-pause{min-width:44px;min-height:44px}.slide-counter{display:none}main a[href]:not(.desk-item),footer a[href]{min-height:44px;display:inline-flex;align-items:center}.news-desk{grid-template-columns:1fr;padding:22px 20px}.desk-kicker,.evidence-key{grid-column:auto}.lead-layout{border-bottom:0}.news-grid{grid-template-columns:1fr}.story.feature{grid-column:auto}.story img,.story.feature img{height:220px}.story{padding-bottom:14px}.method-grid,.lab-grid{grid-template-columns:1fr}.report-map{grid-template-columns:1fr}.report-item,.report-item:nth-child(even){padding:16px 0;border-left:0}.range-scale{grid-template-columns:1fr 1fr}.range:nth-child(2){border-right:0}.range:nth-child(-n+2){border-bottom:1px solid var(--line)}.igl-review,.evidence-review{padding-top:54px}.treatment-detail{grid-template-columns:1fr}.treatment-sources{grid-column:auto}.pipeline{grid-template-columns:1fr}.pipeline article:last-child{grid-column:auto}.testing-note{grid-template-columns:1fr}.source-list.compact{grid-template-columns:1fr}.section-head p{font-size:.86rem}.sponsor-form,.newsletter-form{grid-template-columns:1fr}.sponsor-form .full{grid-column:auto}.footer-bottom{align-items:flex-start;flex-direction:column}.mobile-only{display:inline}
    }
    @media(prefers-reduced-motion:reduce){html{scroll-behavior:auto}*,*::before,*::after{scroll-behavior:auto!important;animation-duration:.01ms!important;animation-iteration-count:1!important;transition-duration:.01ms!important}.hero-slide{transition:none}}
  
    [hidden]{display:none!important}
    .site-nav{position:sticky;top:0;z-index:30;background:var(--surface);border-bottom:1px solid var(--line);box-shadow:0 4px 14px rgba(0,56,102,.07)}
    .site-nav .wrap{display:flex;align-items:center;gap:7px;min-height:56px}
    .site-nav a{min-height:44px;display:inline-flex;align-items:center;padding:7px 9px;color:var(--ink);font-size:.8rem;font-weight:700;text-decoration:none;white-space:nowrap}
    .site-nav a:hover,.site-nav a[aria-current="page"]{color:var(--teal);text-decoration:underline;text-underline-offset:5px;text-decoration-thickness:2px}
    .home-link{margin-right:4px}.nav-links{display:flex;align-items:center;gap:1px}
    /* ---- standout Find a Clinic CTA ---- */
    .site-nav a.clinic-cta,.home-filters a.clinic-cta{display:inline-flex;align-items:center;justify-content:center;min-height:44px;background:#cf5a1a;color:#fff;font-weight:800;font-size:.85rem;padding:10px 20px;border-radius:9px;text-decoration:none;white-space:nowrap;box-shadow:0 2px 10px rgba(207,90,26,.35)}
    .site-nav a.clinic-cta:hover,.home-filters a.clinic-cta:hover,.site-nav a.clinic-cta:focus-visible,.home-filters a.clinic-cta:focus-visible{background:#b34d14;color:#fff;text-decoration:none}
    html[data-theme="dark"] .clinic-cta{background:#ff8a4d;color:#231303}
    html[data-theme="dark"] a.clinic-cta:hover,html[data-theme="dark"] a.clinic-cta:focus-visible{background:#ffa26b;color:#231303}.menu-toggle{display:none;min-height:44px;border:1px solid var(--line);background:var(--surface);color:var(--ink);padding:8px 12px;font-weight:800;cursor:pointer}
    .home-page>.wrap:first-of-type{padding-top:1px}
    .breadcrumb{display:flex;align-items:center;gap:9px;flex-wrap:wrap;padding:24px 0 10px;color:var(--muted);font-size:.8rem}.breadcrumb a{min-height:44px;display:inline-flex;align-items:center;color:var(--teal);font-weight:700;text-underline-offset:3px}.breadcrumb span[aria-current="page"]{color:var(--muted)}
    .landing-head{padding:24px 0 30px;border-bottom:4px solid var(--ink);margin-bottom:28px}.landing-head h1{font-size:clamp(2.35rem,5vw,4.8rem);letter-spacing:-.055em;margin:10px 0 14px}.landing-head p{max-width:68ch;margin:0;color:var(--muted);font-size:1rem}
    .landing-grid,.search-results{display:grid;grid-template-columns:repeat(3,minmax(0,1fr));gap:1px;background:var(--line);border:1px solid var(--line)}
    .route-card{background:var(--surface);padding:23px;min-width:0}.route-card h3{font-size:1.18rem;line-height:1.18;margin:9px 0}.route-card h3 a{text-decoration:none}.route-card h3 a:hover{text-decoration:underline;text-underline-offset:4px}.route-card p{color:var(--muted);font-size:.86rem;margin:0 0 11px}
    .home-top-grid{display:grid;grid-template-columns:repeat(5,minmax(0,1fr));gap:1px;background:var(--line);border:1px solid var(--line)}.home-top-grid .route-card{padding:19px}.home-top-grid .route-card h3{font-size:1rem}
    .desk-overview-grid{display:grid;grid-template-columns:repeat(4,minmax(0,1fr));gap:14px}.desk-overview-card{display:flex;flex-direction:column;min-height:190px;background:var(--surface);padding:22px;text-decoration:none;border-top:4px solid var(--teal)}.desk-overview-card span{font-size:.72rem;color:var(--muted);font-weight:700}.desk-overview-card strong{font-family:"Libre Franklin",sans-serif;font-size:1.35rem;margin:18px 0 8px}.desk-overview-card p{font-size:.82rem;color:var(--muted);margin:0}.desk-overview-card:hover strong{text-decoration:underline;text-underline-offset:4px}
    .clinic-directory{padding-bottom:28px}.clinic-listing{background:var(--surface);border-top:5px solid var(--teal);padding:clamp(24px,4vw,42px);box-shadow:var(--shadow)}.clinic-listing h2{font-size:clamp(1.65rem,3vw,2.5rem);letter-spacing:-.035em;margin:12px 0}.clinic-listing>p{max-width:66ch;color:var(--muted);margin:0 0 28px}.clinic-contact-grid{display:grid;grid-template-columns:1.2fr .8fr 1.2fr;gap:0;border-block:1px solid var(--line)}.clinic-contact{padding:20px 22px 20px 0}.clinic-contact+.clinic-contact{padding-left:22px;border-left:1px solid var(--line)}.clinic-contact b{display:block;font-size:.72rem;letter-spacing:.08em;text-transform:uppercase;color:var(--teal);margin-bottom:7px}.clinic-contact address{font-style:normal}.clinic-contact a{color:var(--teal);font-weight:700;text-underline-offset:3px;overflow-wrap:anywhere}.clinic-coming{margin:28px 0 0;padding-top:20px;border-top:1px solid var(--line);font-family:"Libre Franklin",sans-serif;font-weight:700;color:var(--muted)}
    .home-filters{display:flex;flex-wrap:wrap;gap:7px;margin:-12px 0 22px}.home-filters button{min-height:44px;border:1px solid var(--line);background:var(--surface);color:var(--ink);padding:8px 12px;font-size:.8rem;font-weight:700;cursor:pointer}.home-filters button:hover,.home-filters button.active{background:var(--ink);color:var(--paper)}
    .route-article{padding-top:0;padding-bottom:68px}.route-article>.breadcrumb{width:min(1180px,calc(100% - 40px));margin:0 auto}.route-article:not(.wrap)>:not(.breadcrumb):not(.related):not(.back-top){ }
    .route-article.story,.route-article.treatment-entry,.route-article.watch-card,.route-article.fact,.route-article.pipeline-entry{width:min(900px,calc(100% - 40px));margin:0 auto;padding-top:28px}.route-article.story img,.route-article.watch-card img{max-height:460px;object-fit:cover}.route-article.story h1,.route-article.fact h1,.route-article.treatment-entry h1{font-size:clamp(2rem,4vw,3.5rem);letter-spacing:-.045em;margin:12px 0 16px}.route-article.story p,.route-article.fact p{font-size:1rem}.route-article.treatment-entry{display:grid;padding-bottom:68px}.route-article.treatment-entry .treatment-detail{margin-top:10px}
    .route-article.testing{width:100%;padding-top:0}.route-article.testing>.breadcrumb{color:#c7ded9}.route-article.testing>.breadcrumb a{color:#9ce1d8}.route-article.testing>.wrap{padding-top:28px;padding-bottom:68px}
    .route-article.evidence-review,.route-article.igl-review{padding-top:0}.route-article.evidence-review>header,.route-article.evidence-review>.evidence-body,.route-article.igl-review>header,.route-article.igl-review>.igl-body{width:min(1180px,calc(100% - 40px));margin-left:auto;margin-right:auto}.route-article.evidence-review>header,.route-article.igl-review>header{padding-top:28px}
    .route-article>section:first-of-type{margin-top:28px}.route-article>h1{font-size:clamp(2.1rem,4vw,3.7rem);letter-spacing:-.05em;margin:20px 0}
    .related{width:min(1180px,calc(100% - 40px));margin:48px auto 0;padding-top:26px;border-top:3px solid var(--ink)}.related h2{font-size:1.35rem;margin-bottom:15px}.related-links{display:grid;grid-template-columns:repeat(3,1fr);gap:10px}.related-links a{background:var(--surface-2);padding:14px;min-height:56px;display:flex;align-items:center;color:var(--teal);font-size:.84rem;font-weight:700;text-underline-offset:3px}.back-top{display:block;margin:24px auto 0;min-height:44px;border:1px solid var(--line);background:var(--surface);color:var(--ink);padding:9px 14px;font-weight:800;cursor:pointer}
    @media(max-width:1000px){.site-nav a{font-size:.74rem;padding-inline:6px}.home-top-grid{grid-template-columns:repeat(3,1fr)}.desk-overview-grid{grid-template-columns:repeat(2,1fr)}.landing-grid,.search-results{grid-template-columns:repeat(2,1fr)}}
    @media(max-width:760px){.brand-mast .wrap{padding:9px 0 10px}.brand-mast .brand-home{width:min(100%,300px)}.brand-tagline{font-size:.88rem}.utility .edition{font-size:.72rem}.site-nav .wrap{justify-content:space-between;position:relative}.site-nav .home-link{font-size:.86rem}.menu-toggle{display:inline-flex;align-items:center;gap:8px}.nav-links{display:none;position:absolute;left:0;right:0;top:100%;background:var(--surface);border:1px solid var(--line);box-shadow:var(--shadow);padding:8px;grid-template-columns:1fr 1fr}.nav-links.open{display:grid}.site-nav .nav-links a{font-size:.88rem;padding:11px 13px;border-bottom:1px solid var(--line)}.home-top-grid,.landing-grid,.search-results{grid-template-columns:1fr}.desk-overview-grid{grid-template-columns:1fr 1fr}.desk-overview-card{min-height:160px}.clinic-contact-grid{grid-template-columns:1fr}.clinic-contact{padding:18px 0}.clinic-contact+.clinic-contact{padding-left:0;border-left:0;border-top:1px solid var(--line)}.related-links{grid-template-columns:1fr}.route-article>.breadcrumb,.route-article.evidence-review>header,.route-article.evidence-review>.evidence-body,.route-article.igl-review>header,.route-article.igl-review>.igl-body,.related{width:min(100% - 26px,720px)}.route-article.story,.route-article.treatment-entry,.route-article.watch-card,.route-article.fact,.route-article.pipeline-entry{width:min(100% - 26px,720px)}}
    @media(max-width:460px){.desk-overview-grid{grid-template-columns:1fr}.home-filters{gap:5px}.home-filters button{font-size:.76rem;padding-inline:10px}.brand-tagline{font-size:.82rem}.route-card{padding:19px}}

  
/* ---- multi-page additions ---- */
.page-hero{margin:0 0 1.5rem;border-radius:14px;overflow:hidden;background:#0a2a4a}
.page-hero img{display:block;width:100%;height:auto;max-height:420px;object-fit:cover}
.img-credit{font-size:.78rem;opacity:.75;margin:.4rem 0 0}
.route-article .img-credit,.page-hero .img-credit{padding:0 .25rem}
.site-search{position:relative;min-width:200px;flex:1;max-width:340px}
.site-search input{width:100%;padding:.45rem .8rem;border-radius:999px;border:1px solid rgba(0,96,128,.35);font-size:.9rem;background:#fff;color:#0a2a4a}
[data-theme="dark"] .site-search input{background:#10283f;color:#eef;border-color:#2b4a66}
.site-search-results{position:absolute;top:calc(100% + 6px);left:0;right:0;background:#fff;border:1px solid #cfe3ea;border-radius:10px;box-shadow:0 12px 32px rgba(0,48,96,.18);z-index:60;max-height:320px;overflow:auto}
[data-theme="dark"] .site-search-results{background:#0f2740;border-color:#2b4a66}
.site-search-results a{display:block;padding:.55rem .8rem;text-decoration:none;color:inherit;border-bottom:1px solid #eef3f6}
.site-search-results a:last-child{border-bottom:0}
.site-search-results a:hover,.site-search-results a:focus{background:#eaf6f4}
[data-theme="dark"] .site-search-results a:hover{background:#16334f}
.site-search-results .res-desk{font-size:.72rem;text-transform:uppercase;letter-spacing:.06em;color:#009080}
.site-search-results .res-title{font-weight:600}
.evidence-chart{margin:2rem 0;padding:1.25rem;border:1px solid #cfe3ea;border-radius:12px;background:#f7fcfa}
[data-theme="dark"] .evidence-chart{background:#0e2438;border-color:#2b4a66}
.evidence-chart h3{margin-top:0}
.evidence-chart svg{width:100%;height:auto;display:block}
.evidence-chart figcaption{font-size:.85rem;opacity:.85;margin-top:.6rem}
.faq{margin:2.5rem 0;padding:1.25rem;border-radius:12px;background:#f2f8f7;border:1px solid #d8ebe8}
[data-theme="dark"] .faq{background:#0e2438;border-color:#2b4a66}
.faq-item{margin:1rem 0}
.faq-item h3{margin:.2rem 0 .4rem;font-size:1.02rem}
.med-disclaimer{margin:2rem 0;padding:1rem 1.25rem;border-left:4px solid #009080;background:#f2f8f7;border-radius:0 10px 10px 0;font-size:.9rem}
[data-theme="dark"] .med-disclaimer{background:#0e2438}
.sr-only{position:absolute;width:1px;height:1px;padding:0;margin:-1px;overflow:hidden;clip:rect(0,0,0,0);white-space:nowrap;border:0}
.skip-link{position:absolute;left:-9999px;top:0;background:#009080;color:#fff;padding:.6rem 1rem;z-index:100;border-radius:0 0 8px 0}
.skip-link:focus{left:0}
.back-top{position:fixed;right:1rem;bottom:1rem;z-index:50;border:0;border-radius:999px;padding:.7rem 1rem;background:#003060;color:#fff;cursor:pointer;box-shadow:0 6px 18px rgba(0,48,96,.3);opacity:0;pointer-events:none;transition:opacity .25s}
.back-top.show{opacity:1;pointer-events:auto}
.article-dates{font-size:.85rem;opacity:.8;margin:.4rem 0 1rem}
@media (max-width:760px){.site-search{max-width:none;order:3;flex-basis:100%}.utility-actions{flex-wrap:wrap}}